KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CBX8
All Species:
11.21
Human Site:
S246
Identified Species:
24.67
UniProt:
Q9HC52
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HC52
NP_065700.1
389
43396
S246
G
K
F
P
A
G
H
S
V
I
Q
L
A
R
R
Chimpanzee
Pan troglodytes
XP_523736
378
42282
A244
R
P
P
A
P
I
L
A
P
I
A
G
A
L
F
Rhesus Macaque
Macaca mulatta
XP_001109073
247
28128
R119
Q
D
L
A
S
T
S
R
A
R
E
G
L
R
N
Dog
Lupus familis
XP_850749
379
41955
S236
G
K
F
P
A
G
H
S
V
I
Q
L
A
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXV1
362
39841
S219
G
K
F
P
A
G
H
S
V
I
Q
L
A
R
R
Rat
Rattus norvegicus
P60889
158
17948
K31
G
K
V
E
Y
L
V
K
W
K
G
W
P
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517206
350
37971
P216
A
E
P
S
L
R
L
P
G
G
S
H
W
L
L
Chicken
Gallus gallus
XP_001231757
231
25537
L104
E
G
L
R
N
M
A
L
T
P
Q
G
S
G
S
Frog
Xenopus laevis
NP_001088858
361
41222
T221
Q
L
A
R
R
Q
D
T
E
L
V
S
S
N
Q
Zebra Danio
Brachydanio rerio
Q6PGZ3
629
71992
R391
L
Q
T
T
H
S
R
R
L
P
R
P
S
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26017
390
43958
T243
P
Q
P
T
Q
Q
V
T
P
S
Q
Q
Q
P
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.7
57.3
90.7
N.A.
87.6
24.4
N.A.
34.1
43.1
51.9
22.2
N.A.
24.3
N.A.
N.A.
N.A.
Protein Similarity:
100
68.3
59.9
92.5
N.A.
88.6
31.6
N.A.
44.4
48.5
64.7
34.8
N.A.
41.5
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
6.6
100
N.A.
100
13.3
N.A.
0
6.6
0
0
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
20
100
N.A.
100
20
N.A.
6.6
13.3
26.6
26.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
19
28
0
10
10
10
0
10
0
37
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
10
10
0
10
0
0
0
0
10
0
10
0
0
0
0
% E
% Phe:
0
0
28
0
0
0
0
0
0
0
0
0
0
0
19
% F
% Gly:
37
10
0
0
0
28
0
0
10
10
10
28
0
10
0
% G
% His:
0
0
0
0
10
0
28
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
37
0
0
0
0
0
% I
% Lys:
0
37
0
0
0
0
0
10
0
10
0
0
0
0
10
% K
% Leu:
10
10
19
0
10
10
19
10
10
10
0
28
10
19
10
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
10
% N
% Pro:
10
10
28
28
10
0
0
10
19
19
0
10
10
19
0
% P
% Gln:
19
19
0
0
10
19
0
0
0
0
46
10
10
0
10
% Q
% Arg:
10
0
0
19
10
10
10
19
0
10
10
0
0
37
28
% R
% Ser:
0
0
0
10
10
10
10
28
0
10
10
10
28
10
10
% S
% Thr:
0
0
10
19
0
10
0
19
10
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
19
0
28
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
10
10
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _